Relevant studies
Absence of CNTNAP2 leads to epilepsy, neuronal migration abnormalities and core autism-related deficits" (link)
Meds
Genetic and Functional Analysis of the DLG4 Gene Encoding the Post-Synaptic Density Protein 95 in Schizophrenia" (link)
Glycine transporter I inhibitor, N-Methylglycine (sarcosine), added to antipsychotics for the treatment of schizophrenia (https://www.infona.pl/resource/bwmeta1.element. elsevier-ad6cad94-4db2-3c7c- a082-d18ae6f506ae)
NMDA receptor antagonist effects, cortical glutamatergic function, and schizophrenia: toward a paradigm shift in medication development (http://citeseerx.ist.psu.edu/viewdoc/download?doi=10.1.1. 473.2553&rep=rep1&type=pdf) GABAB-mediated rescue of altered excitatory– inhibitory balance, gamma synchrony and behavioral deficits following constitutive NMDAR-hypofunction (https://www.nature.com/articles/tp201269.pdf)
- D-sarcosine, glycine reduces negative schizophrenia symptoms (https://www.infona.pl/
resource/bwmeta1.element. elsevier-ad6cad94-4db2-3c7c- a082-d18ae6f506ae) op cit (http://journals.plos.org/ plosone/article?id=10.1371/ journal.pone.0015107) - clozapine* reduces social behavior deficit. The ampakines are a new class of promising compounds … It is believed that thesec ompounds may induce less excitotoxicity than drugs that are direct agonists at he NMDA receptor (http://www.schres-journal.
com/article/S0920-9964(01) 00311-5/abstract)(https:// journals.lww.com/neuroreport/ Fulltext/2001/01220/Clozapine, _but_not_haloperidol,_ reverses_social.10.aspx) - Risperdol reduces repetitive behaviors (https://www.sciencedirect.
com/science/article/pii/ S0092867411010105) - baclofen reduces behavioral deficits, symptoms of autism through GABAB rescue of excitatory–inhibitory balance (https://www.nature.
com/articles/tp201269)
Diet:
- Tomatoes, coriander, beetroot (stains kitchenware) for kidneys (https://www.ncbi.nlm.nih.gov/
pubmed/25602702)(http:// citeseerx.ist.psu.edu/viewdoc/ summary?doi=10.1.1.401.8966)(h ttps://www.infona.pl/resource/ bwmeta1.element.elsevier- 653ab9b9-86f9-3f1c-ab8f- 9701332944f2) - Fisetin from strawberries prevent neurological disorders (https://link.springer.com/
article/10.1007/s12035-016- 9795-4) - Omega 3 reduces learning deficits (https://www.liebertpub.com/
doi/abs/10.1089/neu.2004.21. 1457) - Zinc increases BDNF in a protective way and is deficient in kidney impairment (https://www.nature.com/
articles/cddis201073) (http://onlinelibrary.wiley. com/doi/10.1111/jcmm.12239/ full) - Curcumin/turmeric preserves plasticity although also stains kitchenware (https://www.sciencedirect.
com/science/article/pii/ S0014488605003274) - Thyme via linalool to reduces aggression, compare to clozapine (https://www.sciencedirect.
com/science/article/pii/ S0944711309002578) - Passionflower for GABAB effects (http://onlinelibrary.wiley.
com/doi/10.1002/ptr.3352/full)
