Monday, March 26, 2018

CNTNAP2 review (Schizophrenia/Autism)

Relevant studies 

Absence of CNTNAP2 leads to epilepsy, neuronal migration abnormalities and core autism-related deficits" (link)


Genetic and Functional Analysis of the DLG4 Gene Encoding the Post-Synaptic Density Protein 95 in Schizophrenia" (link)

Glycine transporter I inhibitor, N-Methylglycine (sarcosine), added to antipsychotics for the treatment of schizophrenia (https://www.infona.pl/resource/bwmeta1.element.elsevier-ad6cad94-4db2-3c7c-a082-d18ae6f506ae)

NMDA receptor antagonist effects, cortical glutamatergic function, and schizophrenia: toward a paradigm shift in medication development (http://citeseerx.ist.psu.edu/viewdoc/download?doi=10.1.1.473.2553&rep=rep1&type=pdf)
GABAB-mediated rescue of altered excitatory– inhibitory balance, gamma synchrony and behavioral deficits following constitutive NMDAR-hypofunction (https://www.nature.com/articles/tp201269.pdf)
Meds 

Diet:

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