Prader-Willi
Calcium, sea buckthorn, periwinkle, choline, vitamin D, vitamin K, agave, ascorbic acid, sertogenics
|
Gene |
Opposite
effect or gene |
|
||||||||||||||||||||
|
|
Zinc? |
Nutritional supplementation of hop rho iso-alpha acids, berberine, vitamin D3, and vitamin K1 produces a favorable bone biomarker profile supporting healthy bone metabolism in postmenopausal women with metabolic syndrome |
||||||||||||||||||||
|
|
|
|
||||||||||||||||||||
|
Paternal Deletion from Snrpn to Ube3a in the Mouse Causes Hypotonia, Growth Retardation and Partial Lethality and Provides Evidence for a Gene Contributing to Prader-Willi Syndrome |
|
|
||||||||||||||||||||
|
Paternal deletion from Snrpn to Ube3a in the mouse causes hypotonia, growth retardation and... |
|
|
||||||||||||||||||||
|
Angelman and Prader‐Willi syndrome: A magnetic resonance imaging study of differences in... |
|
|
||||||||||||||||||||
|
Small gray matter volume in orbitofrontal cortex in Prader-Willi syndrome: A voxel-based MRI study |
|
|
||||||||||||||||||||
|
|
|
|
||||||||||||||||||||
|
|
|
|
||||||||||||||||||||
|
|
Sea
buckthorn |
|
||||||||||||||||||||
|
|
|
|
||||||||||||||||||||
|
|
PDE1
and Vinpocetine Cheung (1970), Kakiuchi and Yamazaki (1970) simultaneously discovered PDE1 from bovine and rat brains, respectively, a calciprotein constituted of 148 aa, as a thermostable factor named calcium- dependent activator or regulator (CDA or CDR) or phosphodiesterase activating factor (PAF), which binds 4 Ca 2+ mol/mol. This protein, named calmodulin (CaM), was shown to activate cyclic nucleotide phosphodiesterase in a calcium-dependent manner. This discovery allowed characterizing the first eluted fraction of PDE activity (Peak 1 or PDE I) isolated by chromatography from vascular smooth muscle. Since this PDE I fraction was specifically activated by Ca2+/CaM, it was also named CaM- PDE[11]. PDE1 family having three subtypes: PDE1A, PDE1B and PDE1C and these PDE are stimulated by the Ca 2+ -CAM. These enzymes catalyze the hydrolysis of the cAMP and cGMP and were detected in: blood vessels, heart, lung, testes, platelets and lymphocytes. Vinpocetine is a PDE1 inhibitor which inhibit Ca +2 /calmodulin-dependent phosphodiesterase (PDE) type 1. Beside this, like vitamin E, vinpocetine is an effective scavenger of hydroxyl radicals and shown to inhibit lipid peroxidation in synaptosomes of murine brain tissue and to protect against global anoxia and hypoxia in animals. Vinpocetine has been shown to protect neurons from the toxicity of glutamate and Nmethyl-d-aspartate (NMDA), lowers blood viscosity in patients with cerebrovascular disease, has significant vasodilating properties, decreases platelet aggregation, and increasesand maintains erythrocyte flexibility underoxidative stress[12].Vinpocetine iseffective in ameliorating i.c.v. streptozotocin induced behavioural alterations,cholinergic dysfunction and oxidative– nitritive stress. Theobserved beneficial effects of vinpocetine in spatialmemory processingmay be due to its ability to restore cholinergic functions, prevent neuronaldamage and possibly through its antioxidant mechanism [13]. |
|
||||||||||||||||||||
|
|
|
Effects of hormone replacement therapy and aging on cognition: evidence for executive dysfunction
DJ
Wegesin, Y
Stern - Aging, Neuropsychology, and Cognition, 2007 - Taylor &
Francis
...
Ovarian hormones differentially influence immunoreactivity for
dopamine b-hydroxylase, choline acetyltransferase, and
serotonin in the dorsolateral prefrontal cortex of adult
rhesus monkeys. Journal of Comparative Neurology, 409: 438–451.
View all references). ..
|
||||||||||||||||||||
|
|
|
|
||||||||||||||||||||
|
|
|
|
||||||||||||||||||||
|
|
… , vitamin D 3, and vitamin K 1 produces a favorable bone biomarker profile supporting healthy bone metabolism in postmenopausal women with metabolic syndrome
JJ
Lamb, MF Holick, RH Lerman, VR Konda… - Nutrition Research, 2011
- Elsevier
...
any prescription or nonprescription anti-inflammatory drugs;
recent use of the study botanicals; allergy to ... A
second analysis, limited to participants who met the metabolic
syndrome criteria at visit ... analysis, subjects
were stratified by the tertile rank of baseline IGF-I
concentrations. ...
|
Calcium? |
||||||||||||||||||||
|
Neurofilament-2H3
(NF)
1:2000
Monoclonal (mouse IgG) Dev. Studies Hybridoma Bank, Iowa 20
Neurofilament
150 kd
1:2000
Polyclonal (rabbit)
Chemicon,
Temecula, CA
21,
22
Growth-associated
protein 43 (GAP43)
1:2000
Monoclonal (mouse IgG) Sigma, St. Louis, MO
23
Vimentin
40E-C (VIM)
1:200
Monoclonal (mouse IgM) Dev. Studies Hybridoma Bank
24
Transiently
expressed axonal glycoprotein
clone
4D7 (TAG1)
1:200
Monoclonal (mouse IgM) Dev. Studies Hybridoma Bank
20,
25
Substance
P receptor (NK1R)
1:1000
Polyclonal (rabbit)
Advanced
Targeting Systems,
San
Diego, CA
26,
27
Cell
adhesion molecule L1 (L1)
1:200
Monoclonal (rat)
Chemicon
20
Choline
acetyl transferase (ChAT)
1:300
Polyclonal (goat)
Chemicon
28
Substance
P (SubP)
1:500
Monoclonal (rat)
Chemicon
29
Serotonin
(5HT)
1:1000
Goat
Chemicon
30
Somatostatin
(SST)
1:1000
Polyclonal (rabbit)
Immunostar,
Hudson, WI
31
Tyrosine
hydroxylase (TH)
1:2000
Polyclonal (rabbit)
Chemicon
22
|
|
Physiological effects of dietary fructans extracted from Agave tequilana Gto. and Dasylirion spp.
JE
Urias-Silvas, PD
Cani, E Delmée… - British Journal of …, 2008 - Cambridge
Univ Press
...
NM, Cani PD, Daubioul C & Neyrinck AM (2005) Impact of inulin
and oligofructose on gastrointestinal peptides. ...
Williams CM, Roberfroid MB, Thissen JP & Delzenne NM (1998)
Insulin, glucagon-like peptide 1, glucose-dependent
insulinotropic polypeptide and insulin ...
Molecular characterisation of Ltchi7, a gene encoding a Class III endochitinase induced by drought stress in Lotus spp
G
Tapia, L
Morales‐Quintana, L Inostroza… - Plant …, 2011 - Wiley
Online Library
...
2010 German Botanical Society and The Royal Botanical
Society of ... of nodules is tightly regulated by several
factors, such as environmental (nitrate, drought, cold) and
endogenous hormones (Streeter 1988 ... The amino
acid sequence in bold match the deduced signal peptide. ...
|
||||||||||||||||||||
|
Genesis of olfactory receptor neurons in vitro: regulation of progenitor cell divisions by fibroblast growth factors
MK
DeHamer, JL Guevara, K
Hannon, BB Olwin… - Neuron, 1994 - Elsevier
...
Fibroblast growth factors: activities and
significance of non-neurotrophin neurotrophic growth
factors. Curr. Opin. ... Birren et al., 1993; SJ
Birren, L. Lo, DJ Anderson; Sympathetic neuroblasts undergo a
developmental switch in trophic factor dependence. ...
Cited
by 177 Related
articles More
The neurotrophic effects of fibroblast growth factors on dopaminergic neurons in vitro are mediated by mesencephalic glia [published erratum appears in J Neurosci …
J
Engele, MC Bohn - The Journal of neuroscience, 1991 - Soc
Neuroscience
...
is increasing evidence that other known growth factors,
such as fibroblast growth factor (FGF),
affect ... to the stimulation of glial pro- liferation or
whether the growth factors induce synthesis ...
further be excluded that these neurotrophic ac- tivities derive
from fibroblasts or microglia ...
|
[HTML] Ascorbic acid increases the yield of dopaminergic neurons derived from basic fibroblast growth factor expanded mesencephalic precursors
J
Yan, L
Studer, RDG McKay - Journal of neurochemistry, 2001 - Wiley
Online Library
Abstract
CNS precursors derived from E12 rat mesencephalon
proliferate in the presence of basic fibroblast growth factor
and differentiate in vitro into functional dopaminergic
neurons, which upon transplantation alleviate behavioral symptoms
in a rat model of Parkinson's ...
|
|
No comments:
Post a Comment